We present findings from the largest study of intensive BP management in CKD patients. First, BP is harder to manage intensively in this population. Second, primary outcomes are not improved by intensive management of CKD patients, as compared to standard management. Third, intensively managed CKD patients have higher risks of therapy-related adverse events. Therefore, our study cautions physicians against applying the SPRINT-recommended intensive SBP target of <120 to CKD patients.
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