The SPRINT Data Analysis Challenge


SPRINT Data Analysis Challenge

Now Available: Free On-Demand Recording of the Web Event Sessions

Browse the session catalog at to view the recorded sessions and feel free to share the link with any colleagues or peers who would find the discussion of relevance.

Thank you to all SPRINT Challenge participants. We appreciate your interest and the effort that went into each entry.

We are pleased to announce the SPRINT Challenge winners.

View the top three entries and read the novel findings that were identified using the SPRINT trial data. Read more »

Browse all the SPRINT Challenge submissions. Read more »

Thank you to our collaborators: the SPRINT Trial investigators and NHLBI.

We also want to thank the SPRINT trial investigators who worked diligently to release the data underlying the NEJM article one-year in advance and the staff at NHLBI’s BioLINCC depository for all of their collaborative support.

Let’s continue this important conversation.

Join us for the free web event Aligning Incentives for Sharing Clinical Trial Data on April 3–4, 2017. View the SPRINT Challenge winners’ presentations and hear what was learned from the SPRINT Challenge directly from the SPRINT PIs, data analysts, patient participants, and the NHLBI repository. Learn more »


Clinical trials drive medical advances and have a direct impact on health outcomes. Thoughtful, transparent systems for the responsible sharing of clinical trial data are important in maximizing the contribution of the patients who put themselves at risk by participating in clinical trials. The New England Journal of Medicine (NEJM) is committed to working with the global medical community to make the sharing of clinical trial data an effective, efficient and sustainable part of biomedical research.

To initiate an open conversation among researchers, data analysts, and patient participants, NEJM is hosting a web event, Aligning Incentives for Sharing Clinical Trial Data summit, on April 3–4, 2017. Leading up to the event, NEJM is sponsoring a SPRINT Data Analysis Challenge to demonstrate how clinical trial data can be used to identify additional advances in human health.

Are you up to the SPRINT Challenge to explore the potential from sharing clinical trial data? If so, NEJM challenges you to analyze the dataset underlying the SPRINT article — A Randomized Trial of Intensive versus Standard Blood-Pressure Control (N Engl J Med 373: 2103-2116) — and identify a novel scientific or clinical finding to advance medical science.


Register to ‘Follow’ the SPRINT Challenge

All are welcome to register to 'Follow' the SPRINT Challenge. Stay informed of news, updates and important deadlines. Comment on Challenge Round submissions and cast your crowdvote for the best entry.

Apply for the SPRINT Data

Visit the How To Enter page for step-by-step instructions and tips for expediting the data request process, which requires an Institutional Review Board (IRB) approval or exemption certificate, and a data use agreement signed by you and your institution.

Qualifying Round: Answer One Question Using SPRINT Data

The SPRINT data underlying the NEJM article will be made available on November 1, 2016. In the Qualifying Round, reanalyze the SPRINT data to answer one question and progress to the Challenge Round.

Challenge Round: Submit Your Finding Using SPRINT Data

In the Challenge Round, use the SPRINT data and any other publicly available dataset to identify and submit a novel clinical finding.

Make a Difference, Win a Prize, and Gain International Bragging Rights

Take a shot at making a valuable contribution and you could win a prize and a chance to present at the Aligning Incentives for Sharing Clinical Trial Data summit.

Want to stay updated? Follow Contest & Create Submissions